By Tundo P., Perosa A., Zecchini F. (eds.)
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This reference guide is the 1st to supply a accomplished evaluate, systematically characterizing all recognized transporters considering drug removal and resistance. Combining contemporary wisdom on all recognized periods of drug providers, from microbes to guy, it starts off with a glance at human and mammalian transporters.
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52. P. E. Nielsen, M. Egholm, R. H. Berg, O. Buchardt, Science, 254, 1497 (1991). 53. I. Ugi, E. Wischho¨fer, Chem. , 95, 136 (1962). 54. I. Ugi, H. Eckert, Natural Product Chemistry, Vol. 12, pp. 113–143, Science Publ. 1000 AE, Amsterdam, The Netherlands, 1992. 55. C. Burdack, Doctoral Thesis, Technical University of Munich, 2001. 56. C. Hanusch-Kompa, I. , 39, 2725 (1998). 57. C. Hanusch-Kompa, Doctoral Thesis, Technical University of Munich, 1997. 58. J. Zhang, A. Jaconbson, J. R. Rusche, W.
Accordingly, the constituent repeating units of these polysaccharides—glucose (cellulose, starch), fructose (inulin), xylose (hemicelluloses), or disaccharide versions thereof, most notably sucrose—are the actual carbohydrate raw materials for organic chemicals with tailor-made industrial applications: they are inexpensive, ton-scale accessible, and provide a resulting chemistry that is better worked out and more variable than that of their polymers. 1 lists the availability and bulk-quantity prices of the eight least expensive sugars—all well below about E10/kg—as compared to some sugar-derived, naturally occurring compounds and basic chemicals from petrochemical sources.
Although it is a common metabolite formed by plants, animals, and microorganisms, its current commercial production of 15,000 t/y is from petroleum, that is, by hydrogenation of fumaric or maleic acid. The major technical hurdles for succinic acid as a green, renewable, bulk-scale commodity chemical—1,4-butanediol, THF, g-butyrolactone, or pyrrolidones are industrially relevant follow-up products—include the development of a very low-cost fermentation route from sugar feedstocks. 9) include a genetically cloned form of Aspergillus succinoproducens, an engineered E.
Methods and Reagents for Green Chemistry.. An Introduction by Tundo P., Perosa A., Zecchini F. (eds.)