Download PDF by Jean D. Sipe: Amyloid Proteins: The Beta Sheet Conformation and Disease

By Jean D. Sipe

A first-stop reference on proteins linked to amyloidosis. This booklet is the 1st to give a scientific review of all recognized fibril-forming proteins, together with their biochemical features and pathophysiology. It considers the clinically well-known amyloid proteins which are recognized to be linked to the amyloid protein folding issues, facing their universal structural and thermodynamic positive factors that bring about amyloid fibril formation and illness. Emphasis is at the thermodynamics of protein folding, the constitution and physiologic results of universal oligomeric and subfibrillar intermediates and the effect of the extracellular matrix and mobile trafficking and metabolism at the genesis and catabolism of beta pleated sheet proteins. The chapters on particular amyloid proteins all persist with a standard constitution, permitting easy access to the specified biochemical and scientific facts, making this a useful software for clinicians and researchers alike.

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Extra resources for Amyloid Proteins: The Beta Sheet Conformation and Disease

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Shirahama, T. and A. S. Cohen. Intralysosomal formation of amyloid fibrils. Am J Pathol 1975, 81, 101–116. Gueft, B. and J. J. Ghidoni. The site of formation and ultrastructure of amyloid. Am J Pathol 1963, 43, 837–854. Bywaters, E. G. L. Discussion. In Amyloidosis, E. Mandema, L. Ruinen, H. Scholten and A. S. Cohen (eds). Excerpta Medica, Amsterdam, 1968, p. 80. Shirahama, T. and A. S. Cohen. Highresolution electron microscopic analysis 19 20 1 Amyloidosis and Amyloid Proteins: Brief History and Definitions 48 49 50 51 52 53 54 55 56 57 of the amyloid fibril.

Tan, M. Nesheim and R. Kisilevsky. Direct evidence for circulating apoSAA as the precursor of tissue AA amyloid deposits. Scand J Immunol 1988, 28, 317–324. Zschiesche, W. and W. Jakob. Pathology of animal amyloidoses. Pharmacol Ther 1989, 41, 49–83. Johnson, K. , P. Westermark, K. Sletten and T. D. O’Brien. Amyloid proteins and amyloidosis in domestic animals. Amyloid: Int J Exp Clin Invest 1996, 3, 270–289. Maximow, A. Ueber die experimentell hervorgerufene Amyloid-Entartung der 21 22 1 Amyloidosis and Amyloid Proteins: Brief History and Definitions 91 92 93 94 95 96 97 98 99 100 101 Leber.

E. Dwulet, J. Liepnieks and M. D. Benson. Variant apolipoprotein AI as a major constituent of a human hereditary amyloid. Biochem Biophys Res Commun 1988, 156, 762– 768. Benson, M. , J. Liepnieks, M. Yazaki, T. Yamashita, K. Hamidi Asl, B. Guenther and B. Kluve-Beckerman. A new human hereditary amyloidosis: the result of a stop-codon mutation in the apolipoprotein AII gene. Genomics 2001, 72, 272–277. 23 24 1 Amyloidosis and Amyloid Proteins: Brief History and Definitions 129 Benson, M. , J. Liepnieks, T.

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Amyloid Proteins: The Beta Sheet Conformation and Disease by Jean D. Sipe


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