By Karsten Schrör
Written by way of a number one specialist on Aspirin-related examine, this is often the 1st accomplished treaty of the background, pharmacological results and medical functions of 1 of the main winning medicines ever.The textual content is written with a large viewers in brain and to be comfortably comprehensible for clinicians in addition to biomedical researchers and pharmacologists alike. The content material is brand new and contains the most recent result of medical and educational learn, with a balanced view at the disputed homes of this recognized drug.
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Extra info for Acetylsalicylic Acid
Berliner Klinische Wochenschrift, 13, 1–2, 15–16, 99–103. 11 See, G. (1877) Études sur lacide salicylique et les salicylates; traitement du rhumatisme aigu et chronique, de la goutte, et de diverses affections du systeme nerveux sensitif par les salicylates. Bulletin de lAcademie Nationale de Medecine (Paris), 6, 689–706. 717–754. 12 Gordonoff, T. (1965) Zur Geschichte der Antipyrese. Wiener Medizinische Wochenschrift, 115, 45–46. 13 Hangarter, W. (1974) Herkommen, Geschichte, Anwendung und weitere Entwicklung der Salizyls€aure, in Die Salizyls€ aure und ihre Abk€ommlinge (ed.
The classical assays are colorimetric assays, taking advantage from the intense red color of salicylate/ Fe3 þ complexes. The technology is simple and particularly suitable for compliance measurements. Trinder Method The Trinder method  is a colorimetric test where salicylic acid is determined by measuring the absorbance of the ferric ion–salicylate complex after total serum protein is precipitated by mercuric chloride and allowed to react with ferric iron supplied by ferric nitrate. This method involves the generation of a complex between salicylate and ferric ion.
Et al. (1968) The effect of acetylsalicylic acid on platelet function. The Journal of Experimental Medicine, 128, 877–894. J. M. (1967) Impaired platelet–connective tissue reaction in man after aspirin ingestion. The Lancet, 2, 495–497. R. (1968) Effects of salicylates on human platelets. The Lancet, 1, 779–783. M. and Kochwa, S. (1968) The effects of salicylates on the hemostatic properties of platelets in man. The Journal of Clinical Investigation, 47, 2169–2180. B. and Peterson, J. (1968) Inhibition of adenosine diphosphate-induced secondary aggregation and other platelet functions by acetylsalicylic acid ingestion.
Acetylsalicylic Acid by Karsten Schrör