New PDF release: A Primer of Pancreatitis

By Prof. Dr. med. P. G. Lankisch, Prof. Dr. med. M. Büchler, Prof. Dr. med. J. Mössner, Prof. Dr. S. Müller-Lissner (auth.)

ISBN-10: 354063259X

ISBN-13: 9783540632597

ISBN-10: 3642608701

ISBN-13: 9783642608704

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Duodenal ulcer Duodenal ulcers seem to arise more frequently in chronic pancreatitis. This may be explained by relative hypersecretion of acid due to reduced secretion of bicarbonate by the pancreas. Malignancy Chronic pancreatitis is a precancerous state, since the risk of pancreatic and extrapancreatic cancers is slightly increased. 36 Pathogenesis of complications Retroperitonea I spread, asciles, pontaneou drainage into the intestine • bile duct ~ obstructive jaundice, cholangitis • pancreatic duct ~ obstructive pancreatiti • duodenum ~ vomiti ng • colon ~ (sub-)il eus due to ps udocysts or inflammatory well ing of the gland 37 Chronic pancreatitis Incidence, course and prognosis Incidence The incidence of chronic pancreatitis in industrialized countries is about 4-6 per 100,000 inhabitants per year.

As a rule, only pseudocysts of > 5 cm lead to complications. Pseudocysts may also spontaneously become smaller or regress entirely. Duodenal ulcer Duodenal ulcers seem to arise more frequently in chronic pancreatitis. This may be explained by relative hypersecretion of acid due to reduced secretion of bicarbonate by the pancreas. Malignancy Chronic pancreatitis is a precancerous state, since the risk of pancreatic and extrapancreatic cancers is slightly increased. 36 Pathogenesis of complications Retroperitonea I spread, asciles, pontaneou drainage into the intestine • bile duct ~ obstructive jaundice, cholangitis • pancreatic duct ~ obstructive pancreatiti • duodenum ~ vomiti ng • colon ~ (sub-)il eus due to ps udocysts or inflammatory well ing of the gland 37 Chronic pancreatitis Incidence, course and prognosis Incidence The incidence of chronic pancreatitis in industrialized countries is about 4-6 per 100,000 inhabitants per year.

Particles smaller than 2 mm are emptied from the stomach together with the food in the digestive phase. To ensure simultaneous emptying of the enzymes with the chyme, preparations with smaller particle sizes should be preferred. Enzyme preparations containing bile acids should be avoided since, at the high doses often required with enzyme preparations, bile acids can lead to chologenic diarrhoea. Ph. units per dayl. Depending on the preparation in question, this corresponds to 2-4 capsules with each main meal and 1-2 capsules with each snack.

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A Primer of Pancreatitis by Prof. Dr. med. P. G. Lankisch, Prof. Dr. med. M. Büchler, Prof. Dr. med. J. Mössner, Prof. Dr. S. Müller-Lissner (auth.)


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